Impact of the Central Polypurine Tract on the Kinetics of Human Immunodeficiency Virus Type 1 Vector Transduction

Lentiviral vectors derived from human immunodeficiency virus type 1 (HIV-1) show great promise as gene carriers for future gene therapy. Insertion of a fragment containing the central polypurine tract (cPPT) in HIV-1 vector constructs is known to enhance transduction efficiency drastically, reported...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Van Maele, Bénédicte, De Rijck, Jan, De Clercq, Erik, Debyser, Zeger
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2003
Предметы:	Gene Therapy
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663775/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.4685-4694.2003
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