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A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo

Mathematical models provide an understanding of in vivo replication kinetics of human immunodeficiency virus type 1 (HIV-1). With a novel intervention designed for increased potency, we have more accurately deduced the half-lives of virus-producing CD4(+) T cells, 0.7 day, and the generation time of...

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Udgivet i:J Virol
Principais autores: Markowitz, Martin, Louie, Michael, Hurley, Arlene, Sun, Eugene, Di Mascio, Michele, Perelson, Alan S., Ho, David D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.5037-5038.2003
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