A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo

Mathematical models provide an understanding of in vivo replication kinetics of human immunodeficiency virus type 1 (HIV-1). With a novel intervention designed for increased potency, we have more accurately deduced the half-lives of virus-producing CD4(+) T cells, 0.7 day, and the generation time of...

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Main Authors: Markowitz, Martin, Louie, Michael, Hurley, Arlene, Sun, Eugene, Di Mascio, Michele, Perelson, Alan S., Ho, David D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC152136/
https://ncbi.nlm.nih.gov/pubmed/12663814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.5037-5038.2003
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