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Human Cytomegalovirus US3 Chimeras Containing US2 Cytosolic Residues Acquire Major Histocompatibility Class I and II Protein Degradation Properties

Human cytomegalovirus (HCMV) glycoprotein US2 increases the proteasome-mediated degradation of major histocompatibility complex (MHC) class I heavy chain (HC), class II DR-α and DM-α proteins, and HFE, a nonclassical MHC protein. US2-initiated degradation of MHC proteins apparently involves the recr...

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Udgivet i:J Virol
Principais autores: Chevalier, Mathieu S., Johnson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152132/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663780/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.4731-4738.2003
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