Human Cytomegalovirus US3 Chimeras Containing US2 Cytosolic Residues Acquire Major Histocompatibility Class I and II Protein Degradation Properties

Human cytomegalovirus (HCMV) glycoprotein US2 increases the proteasome-mediated degradation of major histocompatibility complex (MHC) class I heavy chain (HC), class II DR-α and DM-α proteins, and HFE, a nonclassical MHC protein. US2-initiated degradation of MHC proteins apparently involves the recr...

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Detalles Bibliográficos
Main Authors: Chevalier, Mathieu S., Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152132/
https://ncbi.nlm.nih.gov/pubmed/12663780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.8.4731-4738.2003
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