Human Rhinovirus 2A Proteinase Cleavage Sites in Eukaryotic Initiation Factors (eIF) 4GI and eIF4GII Are Different

Several picornaviruses shut down host cellular protein synthesis by proteolytic cleavage of the eukaryotic initiation factor (eIF) 4GI and eIF4GII isoforms. Viral RNA translation is maintained by a cap-independent mechanism. Here, we identify the human rhinovirus 2 2A(pro) cleavage site in eIF4GII i...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gradi, Alessandra, Svitkin, Yuri V., Sommergruber, Wolfgang, Imataka, Hiroaki, Morino, Shigenobu, Skern, Tim, Sonenberg, Nahum
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12663812/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.8.5026-5029.2003
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