Synergistic Protection of Mice against Plague with Monoclonal Antibodies Specific for the F1 and V Antigens of Yersinia pestis

Monoclonal antibodies specific for Yersinia pestis V antigen and F1 antigen, administered singly or in combination, protected mice in models of bubonic and pneumonic plague. Antibodies showed synergy when administered prophylactically and as a therapy 48 h postinfection. Monoclonal antibodies theref...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Hill, Jim, Copse, Catherine, Leary, Sophie, Stagg, Anthony J., Williamson, E. Diane, Titball, Richard W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.2234-2238.2003
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