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Signaling through the T1/ST2 Molecule Is Not Necessary for Th2 Differentiation but Is Important for the Regulation of Type 1 Responses in Nonhealing Leishmania major Infection

T1/ST2 is a stable cell surface marker selectively expressed on type 2 T helper (Th2) effector cells. Since nonhealing Leishmania major infections in susceptible BALB/c mice have been ascribed to a polarized Th2 response, we used an anti-T1/ST2 monoclonal antibody (MAb) or a T1-Fc fusion protein to...

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Main Authors: Kropf, P., Herath, S., Klemenz, R., Müller, I.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC152039/
https://ncbi.nlm.nih.gov/pubmed/12654814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1961-1971.2003
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