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High Levels of Susceptibility and T Helper 2 Response in MyD88-Deficient Mice Infected with Leishmania major Are Interleukin-4 Dependent

Myeloid differentiation protein 88 (MyD88) is a general adaptor for the signaling cascade through receptors of the Toll/IL-1R family. When infected with Leishmania major parasites, MyD88-deficient mice displayed a dramatically enhanced parasite burden in their tissues similar to that found in suscep...

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Détails bibliographiques
Auteurs principaux: Debus, Andrea, Gläsner, Joachim, Röllinghoff, Martin, Gessner, André
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC308890/
https://ncbi.nlm.nih.gov/pubmed/14638820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.12.7215-7218.2003
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