Resistance to Acute Babesiosis Is Associated with Interleukin-12- and Gamma Interferon-Mediated Responses and Requires Macrophages and Natural Killer Cells

We examined the role of the cytokines gamma interferon (IFN-γ) and interleukin-12 (IL-12) in the model of acute babesiosis with the WA1 Babesia. Mice genetically deficient in IFN-γ-mediated responses (IFNGR2KO mice) and IL-12-mediated responses (Stat4KO mice) were infected with the WA1 Babesia, and...

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Бібліографічні деталі
Опубліковано в::	Infect Immun
Автори:	Aguilar-Delfin, Irma, Wettstein, Peter J., Persing, David H.
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2003
Предмети:	Fungal and Parasitic Infections
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12654819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.4.2002-2008.2003
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Resistance to Acute Babesiosis Is Associated with Interleukin-12- and Gamma Interferon-Mediated Responses and Requires Macrophages and Natural Killer Cells

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