Resistance to Acute Babesiosis Is Associated with Interleukin-12- and Gamma Interferon-Mediated Responses and Requires Macrophages and Natural Killer Cells

We examined the role of the cytokines gamma interferon (IFN-γ) and interleukin-12 (IL-12) in the model of acute babesiosis with the WA1 Babesia. Mice genetically deficient in IFN-γ-mediated responses (IFNGR2KO mice) and IL-12-mediated responses (Stat4KO mice) were infected with the WA1 Babesia, and...

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Detalhes bibliográficos
Main Authors: Aguilar-Delfin, Irma, Wettstein, Peter J., Persing, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152030/
https://ncbi.nlm.nih.gov/pubmed/12654819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2002-2008.2003
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