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Purification of serine racemase: Biosynthesis of the neuromodulator d-serine

High levels of d-serine occur in mammalian brain, where it appears to be an endogenous ligand of the glycine site of N-methyl-d-aspartate receptors. In glial cultures of rat cerebral cortex, d-serine is enriched in type II astrocytes and is released upon stimulation with agonists of non-N-methyl-d-a...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wolosker, Herman, Sheth, Kevin N., Takahashi, Masaaki, Mothet, Jean-Pierre, Brady, Roscoe O., Ferris, Christopher D., Snyder, Solomon H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892700/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.721
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