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Purification of serine racemase: Biosynthesis of the neuromodulator d-serine

High levels of d-serine occur in mammalian brain, where it appears to be an endogenous ligand of the glycine site of N-methyl-d-aspartate receptors. In glial cultures of rat cerebral cortex, d-serine is enriched in type II astrocytes and is released upon stimulation with agonists of non-N-methyl-d-a...

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Bibliografiske detaljer
Main Authors: Wolosker, Herman, Sheth, Kevin N., Takahashi, Masaaki, Mothet, Jean-Pierre, Brady, Roscoe O., Ferris, Christopher D., Snyder, Solomon H.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15203/
https://ncbi.nlm.nih.gov/pubmed/9892700
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