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Metabolic Flux in Both the Purine Mononucleotide and Histidine Biosynthetic Pathways Can Influence Synthesis of the Hydroxymethyl Pyrimidine Moiety of Thiamine in Salmonella enterica

Together, the biosyntheses of histidine, purines, and thiamine pyrophosphate (TPP) contain examples of convergent, divergent, and regulatory pathway integration. Mutations in two purine biosynthetic genes (purI and purH) affect TPP biosynthesis due to flux through the purine and histidine pathways....

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Detalles Bibliográficos
Publicado en:J Bacteriol
Principais autores: Allen, Shara, Zilles, Julie L., Downs, Diana M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151968/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12399482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.22.6130-6137.2002
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