Metabolic Flux in Both the Purine Mononucleotide and Histidine Biosynthetic Pathways Can Influence Synthesis of the Hydroxymethyl Pyrimidine Moiety of Thiamine in Salmonella enterica

Together, the biosyntheses of histidine, purines, and thiamine pyrophosphate (TPP) contain examples of convergent, divergent, and regulatory pathway integration. Mutations in two purine biosynthetic genes (purI and purH) affect TPP biosynthesis due to flux through the purine and histidine pathways....

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Allen, Shara, Zilles, Julie L., Downs, Diana M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151968/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12399482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.22.6130-6137.2002
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