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Role of proto-oncogene activation in carcinogenesis.

The accumulation of genetic damage in the forms of activated proto-oncogenes and inactivated tumor-suppressor genes is the driving force in the evolution of a normal cell to a malignant cell. For example, both the activation of ras oncogenes and the inactivation of several suppressor genes, includin...

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Bibliografske podrobnosti
Main Authors: Anderson, M W, Reynolds, S H, You, M, Maronpot, R M
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1519627/
https://ncbi.nlm.nih.gov/pubmed/1486840
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