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Oncogene activation in spontaneous and chemically induced rodent tumors: implications for risk analysis.

The validity of rodent tumor end points in assessing the potential hazards of chemical exposure to humans is a somewhat controversial but very important issue since most chemicals are classified as potentially hazardous to humans on the basis of long-term carcinogenesis studies in rodents. The abili...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reynolds, S H, Stowers, S J, Patterson, R M, Maronpot, R R, Anderson, M W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474622/
https://ncbi.nlm.nih.gov/pubmed/3203636
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