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Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice

Leptin controls feeding behavior and insulin secretion from pancreatic β-cells. Insulin stimulates the production of leptin, thereby establishing an adipoinsular axis. Earlier we identified leptin receptors on pancreatic β-cells and showed leptin-mediated inhibition of insulin secretion by activatio...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seufert, Jochen, Kieffer, Timothy J., Habener, Joel F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC15195/
https://ncbi.nlm.nih.gov/pubmed/9892692
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