Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
Studies in human systemic lupus erythematosus (SLE) suggest a possible role for histone deacetylases (HDACs) in skewed gene expression and disease pathogenesis. We used the MRL-lpr/lpr murine model of lupus to demonstrate that HDACs play a key role in the heightened levels of both Th1 and Th2 cytoki...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Principais autores: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2003
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588892/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16153 |
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