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Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor–1 (Pref-1)

Preadipocyte factor-1 (Pref-1) is a transmembrane protein highly expressed in preadipocytes. Pref-1 expression is, however, completely abolished in adipocytes. The extracellular domain of Pref-1 undergoes two proteolytic cleavage events that generate 50 and 25 kDa soluble products. To understand the...

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Detalhes bibliográficos
Main Authors: Lee, Kichoon, Villena, Josep A., Moon, Yang Soo, Kim, Kee-Hong, Lee, Sunjoo, Kang, Chulho, Sul, Hei Sook
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151920/
https://ncbi.nlm.nih.gov/pubmed/12588883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315924
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