IL-12 is required for differentiation of pathogenic CD8(+) T cell effectors that cause myocarditis

Cardiac antigen–specific CD8(+) T cells are involved in the autoimmune component of human myocarditis. Here, we studied the differentiation and migration of pathogenic CD8(+) T cell effector cells in a new mouse model of autoimmune myocarditis. A transgenic mouse line was derived that expresses card...

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Detalhes bibliográficos
Main Authors: Grabie, Nir, Delfs, Michael W., Westrich, Jason R., Love, Victoria A., Stavrakis, George, Ahmad, Ferhaan, Seidman, Christine E., Seidman, Jonathan G., Lichtman, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151896/
https://ncbi.nlm.nih.gov/pubmed/12618521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316867
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