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Targeting lentiviral vectors to specific cell types in vivo

We have developed an efficient method to target lentivirus-mediated gene transduction to a desired cell type. It involves incorporation of antibody and fusogenic protein as two distinct molecules into the lentiviral surface. The fusogen is constructed by modifying viral envelope proteins, so that th...

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Detalhes bibliográficos
Main Authors: Yang, Lili, Bailey, Leslie, Baltimore, David, Wang, Pin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518805/
https://ncbi.nlm.nih.gov/pubmed/16864770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604993103
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