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Targeting lentiviral vectors to specific cell types in vivo

We have developed an efficient method to target lentivirus-mediated gene transduction to a desired cell type. It involves incorporation of antibody and fusogenic protein as two distinct molecules into the lentiviral surface. The fusogen is constructed by modifying viral envelope proteins, so that th...

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Bibliografiske detaljer
Main Authors: Yang, Lili, Bailey, Leslie, Baltimore, David, Wang, Pin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518805/
https://ncbi.nlm.nih.gov/pubmed/16864770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604993103
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