Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

Autoimmune (type 1) diabetes mellitus results from the destruction of insulin-producing pancreatic β cells by T lymphocytes. Prediction of cell-mediated autoimmune diseases by direct detection of autoreactive T cells in peripheral blood has proved elusive, in part because of their low frequency and...

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Hauptverfasser: Trudeau, Jacqueline D., Kelly-Smith, Carolyn, Verchere, C. Bruce, Elliott, John F., Dutz, Jan P., Finegood, Diane T., Santamaria, Pere, Tan, Rusung
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151866/
https://ncbi.nlm.nih.gov/pubmed/12531877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316409
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