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Re-Programming Autoreactive T Cells Into T-Regulatory Type 1 Cells for the Treatment of Autoimmunity

Systemic delivery of peptide-major histocompatibility complex (pMHC) class II-based nanomedicines can re-program cognate autoantigen-experienced CD4+ T cells into disease-suppressing T-regulatory type 1 (TR1)-like cells. In turn, these TR1-like cells trigger the formation of complex regulatory cell...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Solé, Patricia, Santamaria, Pere
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320845/
https://ncbi.nlm.nih.gov/pubmed/34335585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.684240
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