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A Finite Element Framework for Studying the Mechanical Response of Macromolecules: Application to the Gating of the Mechanosensitive Channel MscL

The gating pathways of mechanosensitive channels of large conductance (MscL) in two bacteria (Mycobacterium tuberculosis and Escherichia coli) are studied using the finite element method. The phenomenological model treats transmembrane helices as elastic rods and the lipid membrane as an elastic she...

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Bibliografiske detaljer
Main Authors: Tang, Yuye, Cao, Guoxin, Chen, Xi, Yoo, Jejoong, Yethiraj, Arun, Cui, Qiang
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1518658/
https://ncbi.nlm.nih.gov/pubmed/16731564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085985
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