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Gating Mechanisms of Mechanosensitive Channels of Large Conductance, I: A Continuum Mechanics-Based Hierarchical Framework

A hierarchical simulation framework that integrates information from molecular dynamics (MD) simulations into a continuum model is established to study the mechanical response of mechanosensitive channel of large-conductance (MscL) using the finite element method (FEM). The proposed MD-decorated FEM...

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Detalhes bibliográficos
Main Authors: Chen, Xi, Cui, Qiang, Tang, Yuye, Yoo, Jejoong, Yethiraj, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440431/
https://ncbi.nlm.nih.gov/pubmed/18390626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.128488
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