DNA methylation in transcriptional repression of two differentially expressed X-linked genes, GPC3 and SYBL1

Methylation of CpG islands is an established transcriptional repressive mechanism and is a feature of silencing in X chromosome inactivation. Housekeeping genes that are subject to X inactivation exhibit differential methylation of their CpG islands such that the inactive alleles are hypermethylated...

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Bibliographic Details
Main Authors: Huber, Reid, Hansen, R. Scott, Strazzullo, Maria, Pengue, Gina, Mazzarella, Richard, D’Urso, Michele, Schlessinger, David, Pilia, Giuseppe, Gartler, Stanley M., D’Esposito, Maurizio
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC15185/
https://ncbi.nlm.nih.gov/pubmed/9892682
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