New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster

The genomic rate and distribution of effects of deleterious mutations are important parameters in evolutionary theory. The most detailed information comes from the work of Mukai and Ohnishi, who allowed mutations to accumulate on Drosophila melanogaster second chromosomes, shielded from selection an...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Fry, James D., Keightley, Peter D., Heinsohn, Stefanie L., Nuzhdin, Sergey V.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1999
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.574
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