New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster

The genomic rate and distribution of effects of deleterious mutations are important parameters in evolutionary theory. The most detailed information comes from the work of Mukai and Ohnishi, who allowed mutations to accumulate on Drosophila melanogaster second chromosomes, shielded from selection an...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Fry, James D., Keightley, Peter D., Heinsohn, Stefanie L., Nuzhdin, Sergey V.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1999
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.574
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