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New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster

The genomic rate and distribution of effects of deleterious mutations are important parameters in evolutionary theory. The most detailed information comes from the work of Mukai and Ohnishi, who allowed mutations to accumulate on Drosophila melanogaster second chromosomes, shielded from selection an...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Fry, James D., Keightley, Peter D., Heinsohn, Stefanie L., Nuzhdin, Sergey V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15178/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.574
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