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Two Mechanisms for Human Immunodeficiency Virus Type 1 Inhibition by N-Terminal Modifications of RANTES

C-C chemokine receptor 5 (CCR5) is the primary coreceptor for human immunodeficiency virus type 1 (HIV-1) infection. Native chemokines that bind to CCR5 inhibit HIV-1 infection, albeit weakly, but chemically modified chemokines inhibit infection more efficiently. We have investigated the inhibitory...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Pastore, Cristina, Picchio, Gastón R., Galimi, Francesco, Fish, Richard, Hartley, Oliver, Offord, Robin E., Mosier, Donald E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.509-517.2003
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