Fosmidomycin, a Novel Chemotherapeutic Agent for Malaria
In previous studies, fosmidomycin has been shown to possess activity against Plasmodium falciparum in vitro and in the mouse model. It has a novel mode of action through inhibition of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, an enzyme of the nonmevalonate pathway of isoprenoid biosynthesis,...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151759/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.735-738.2003 |
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