Fosmidomycin, a Novel Chemotherapeutic Agent for Malaria

In previous studies, fosmidomycin has been shown to possess activity against Plasmodium falciparum in vitro and in the mouse model. It has a novel mode of action through inhibition of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, an enzyme of the nonmevalonate pathway of isoprenoid biosynthesis,...

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Detaylı Bibliyografya
Asıl Yazarlar: Lell, Bertrand, Ruangweerayut, Ronnatrai, Wiesner, Jochen, Missinou, Michel Anoumou, Schindler, Andreas, Baranek, Thomas, Hintz, Martin, Hutchinson, David, Jomaa, Hassan, Kremsner, Peter Gottfried
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Clinical Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC151759/
https://ncbi.nlm.nih.gov/pubmed/12543685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.735-738.2003
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