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Fosmidomycin, a Novel Chemotherapeutic Agent for Malaria
In previous studies, fosmidomycin has been shown to possess activity against Plasmodium falciparum in vitro and in the mouse model. It has a novel mode of action through inhibition of 1-deoxy-d-xylulose 5-phosphate reductoisomerase, an enzyme of the nonmevalonate pathway of isoprenoid biosynthesis,...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151759/ https://ncbi.nlm.nih.gov/pubmed/12543685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.735-738.2003 |
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