Influence of Macrolide Susceptibility on Efficacies of Clarithromycin and Azithromycin against Streptococcus pneumoniae in a Murine Lung Infection Model

We evaluated the activities of clarithromycin and azithromycin against 19 isolates of Streptococcus pneumoniae using a neutropenic lung infection model. The isolates included five susceptible isolates (clarithromycin and azithromycin MICs, ≤0.12 μg/ml), nine isolates exhibiting low-level, mefA-media...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hoffman, Holly L., Klepser, Michael E., Ernst, Erika J., Petzold, C. Rosemarie, Sa'adah, Loai Mohammed, Doern, Gary V.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Experimental Therapeutics
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12543686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.2.739-746.2003
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!