Influence of Macrolide Susceptibility on Efficacies of Clarithromycin and Azithromycin against Streptococcus pneumoniae in a Murine Lung Infection Model

We evaluated the activities of clarithromycin and azithromycin against 19 isolates of Streptococcus pneumoniae using a neutropenic lung infection model. The isolates included five susceptible isolates (clarithromycin and azithromycin MICs, ≤0.12 μg/ml), nine isolates exhibiting low-level, mefA-media...

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Detalhes bibliográficos
Main Authors: Hoffman, Holly L., Klepser, Michael E., Ernst, Erika J., Petzold, C. Rosemarie, Sa'adah, Loai Mohammed, Doern, Gary V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151733/
https://ncbi.nlm.nih.gov/pubmed/12543686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.2.739-746.2003
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