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Nob1p Is Required for Cleavage of the 3′ End of 18S rRNA

We report the characterization of a novel factor, Nob1p (Yor056c), which is essential for the synthesis of 40S ribosome subunits. Genetic depletion of Nob1p strongly inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, leading to the accumulation of high levels of the 20S pre-rRNA tog...

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Udgivet i:Mol Cell Biol
Principais autores: Fatica, Alessandro, Oeffinger, Marlene, Dlakić, Mensur, Tollervey, David
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588997/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1798-1807.2003
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