Nob1p Is Required for Cleavage of the 3′ End of 18S rRNA

We report the characterization of a novel factor, Nob1p (Yor056c), which is essential for the synthesis of 40S ribosome subunits. Genetic depletion of Nob1p strongly inhibits the processing of the 20S pre-rRNA to the mature 18S rRNA, leading to the accumulation of high levels of the 20S pre-rRNA tog...

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Detalhes bibliográficos
Main Authors: Fatica, Alessandro, Oeffinger, Marlene, Dlakić, Mensur, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC151717/
https://ncbi.nlm.nih.gov/pubmed/12588997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1798-1807.2003
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