Overexpression of Kinase Suppressor of Ras Upregulates the High-Molecular-Weight Tropomyosin Isoforms in ras-Transformed NIH 3T3 Fibroblasts

The down-regulation of the high-molecular-weight isoforms of tropomyosin (TM) is considered to be an essential event in cellular transformation. In ras-transformed fibroblasts, the suppression of TM is dependent on the activity of the Raf-1 kinase; however, the requirement for other downstream effec...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Janssen, Richard A. J., Kim, Phillia N., Mier, James W., Morrison, Deborah K.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2003
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151698/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12588996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.5.1786-1797.2003
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