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Triple Decoding of Hepatitis C Virus RNA by Programmed Translational Frameshifting

Ribosomes can be programmed to shift from one reading frame to another during translation. Hepatitis C virus (HCV) uses such a mechanism to produce F protein from the −2/+1 reading frame. We now report that the HCV frameshift signal can mediate the synthesis of the core protein of the zero frame, th...

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Bibliographic Details
Main Authors: Choi, Jinah, Xu, Zhenming, Ou, Jing-hsiung
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC151691/
https://ncbi.nlm.nih.gov/pubmed/12588970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.5.1489-1497.2003
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