Collagen-binding integrin α(1)β(1) regulates intestinal inflammation in experimental colitis

Central to inflammatory responses are the integrin-mediated adhesive interactions of cells with their ECM-rich environment. We investigated the role of the collagen-binding integrin α(1)β(1) in intestinal inflammation using the mouse model of colitis induced by dextran sodium sulfate (DSS). mAb’s di...

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Main Authors: Krieglstein, Christian F., Cerwinka, Wolfgang H., Sprague, Andrew G., Laroux, F. Stephen, Grisham, Matthew B., Koteliansky, Victor E., Senninger, Norbert, Granger, D. Neil, de Fougerolles, Antonin R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2002
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151649/
https://ncbi.nlm.nih.gov/pubmed/12488427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200215256
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