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A direct role for arrestins in desensitization of the luteinizing hormone/choriogonadotropin receptor in porcine ovarian follicular membranes

The luteinizing hormone/choriogonadotropin (LH/CG) receptor (R) is a heptahelical R that, upon agonist binding, activates the stimulatory guanine nucleotide-binding protein (G(s)) and the downstream effector adenylyl cyclase (AC). Like other G protein-coupled Rs, the LH/CG R subsequently exhibits re...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mukherjee, Sutapa, Palczewski, Krzysztof, Gurevich, Vsevolod, Benovic, Jeffrey L., Banga, J. Paul, Hunzicker-Dunn, Mary
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15164/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.493
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