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Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

BACKGROUND: The eukaryotic RNA-dependent RNA polymerase (RDRP) is involved in the amplification of regulatory microRNAs during post-transcriptional gene silencing. This enzyme is highly conserved in most eukaryotes but is missing in archaea and bacteria. No evolutionary relationship between RDRP and...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Principais autores: Iyer, Lakshminarayan M, Koonin, Eugene V, Aravind, L
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12553882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6807-3-1
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