Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases

BACKGROUND: The eukaryotic RNA-dependent RNA polymerase (RDRP) is involved in the amplification of regulatory microRNAs during post-transcriptional gene silencing. This enzyme is highly conserved in most eukaryotes but is missing in archaea and bacteria. No evolutionary relationship between RDRP and...

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Bibliografiske detaljer

Udgivet i:	BMC Struct Biol
Principais autores:	Iyer, Lakshminarayan M, Koonin, Eugene V, Aravind, L
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2003
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12553882/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6807-3-1
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