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Essential Roles for GPI-anchored Proteins in African Trypanosomes Revealed Using Mutants Deficient in GPI8

The survival of Trypanosoma brucei, the causative agent of Sleeping Sickness and Nagana, is facilitated by the expression of a dense surface coat of glycosylphosphatidylinositol (GPI)-anchored proteins in both its mammalian and tsetse fly hosts. We have characterized T. brucei GPI8, the gene encodin...

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Udgivet i:Mol Biol Cell
Principais autores: Lillico, Simon, Field, Mark C., Blundell, Pat, Coombs, Graham H., Mottram, Jeremy C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2003
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151589/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12631733/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-03-0167
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