A defect in glycosylphosphatidylinositol (GPI) transamidase activity in mutant K cells is responsible for their inability to display GPI surface proteins.

The final step in the pathway that provides for glycosylphosphatidylinositol (GPI) anchoring of cell-surface proteins occurs in the lumen of the endoplasmic reticulum and consists of a transamidation reaction in which fully assembled GPI anchor donors are substituted for specific COOH-terminal signa...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, R, Udenfriend, S, Prince, G M, Maxwell, S E, Ramalingam, S, Gerber, L D, Knez, J, Medof, M E
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC39786/
https://ncbi.nlm.nih.gov/pubmed/8637863
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