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Trapping of megabase-sized DNA molecules during agarose gel electrophoresis

Megabase DNA molecules become trapped in agarose gels during electrophoresis if the electric field exceeds a few volts per cm. Fluorescence microscopy reveals that these molecules invariably arrest in U-shaped conformations. The field-vs.-size dependence for trapping indicates that a critical molecu...

詳細記述

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書誌詳細
主要な著者: Gurrieri, Sergio, Smith, Steven B., Bustamante, Carlos
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC15157/
https://ncbi.nlm.nih.gov/pubmed/9892654
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