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Regulation of Tumor Necrosis Factor Alpha Gene Expression by Mycobacteria Involves the Assembly of a Unique Enhanceosome Dependent on the Coactivator Proteins CBP/p300

Tumor necrosis factor alpha (TNF-α) plays an important role in host containment of infection by Mycobacterium tuberculosis, one of the leading causes of death by an infectious agent globally. Using the pathogenic M. tuberculosis strain H37Rv, we present evidence that upon stimulation of monocytic ce...

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Enregistré dans:
Publié dans:Mol Cell Biol
Auteurs principaux: Barthel, Robert, Tsytsykova, Alla V., Barczak, Amy K., Tsai, Eunice Y., Dascher, Christopher C., Brenner, Michael B., Goldfeld, Anne E.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2003
Sujets:
Transcriptional Regulation
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151551/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.526-533.2003
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