The Ras/Raf/MEK/Extracellular Signal-Regulated Kinase Pathway Induces Autocrine-Paracrine Growth Inhibition via the Leukemia Inhibitory Factor/JAK/STAT Pathway

Sustained activation of the Ras/Raf/MEK/extracellular signal-regulated kinase (ERK) pathway can lead to cell cycle arrest in many cell types. We have found, with human medullary thyroid cancer (MTC) cells, that activated Ras or c-Raf-1 can induce growth arrest by producing and secreting an autocrine...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Park, Jong-In, Strock, Christopher J., Ball, Douglas W., Nelkin, Barry D.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509453/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.543-554.2003
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