Enhanced Genomic Instability and Defective Postreplication Repair in RAD18 Knockout Mouse Embryonic Stem Cells

In lower eukaryotes, Rad18 plays a crucial role in postreplication repair. Previously, we isolated a human homologue of RAD18 (hRAD18) and showed that human cells overexpressing hRad18 protein with a mutation in the RING finger motif are defective in postreplication repair. Here, we report the const...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Tateishi, Satoshi, Niwa, Hitoshi, Miyazaki, Jun-Ichi, Fujimoto, Shiho, Inoue, Hirokazu, Yamaizumi, Masaru
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 2003
Aiheet:	DNA Dynamics and Chromosome Structure
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12509447/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.2.474-481.2003
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