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Ends-out, or replacement, gene targeting in Drosophila
Ends-in and ends-out refer to the two arrangements of donor DNA that can be used for gene targeting. Both have been used for targeted mutagenesis, but require donors of differing design. Ends-out targeting is more frequently used in mice and yeast because it gives a straightforward route to replace...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151379/ https://ncbi.nlm.nih.gov/pubmed/12589026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0535280100 |
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