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Ends-out, or replacement, gene targeting in Drosophila

Ends-in and ends-out refer to the two arrangements of donor DNA that can be used for gene targeting. Both have been used for targeted mutagenesis, but require donors of differing design. Ends-out targeting is more frequently used in mice and yeast because it gives a straightforward route to replace...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gong, Wei J., Golic, Kent G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC151379/
https://ncbi.nlm.nih.gov/pubmed/12589026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0535280100
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